Get access
Advertisement

Asymmetric Aldol Reaction of Glyoxal Catalyzed by Diarylprolinol

Authors


Abstract

original image

All selection should be this­ eeasy: The direct asymmetric aldol reaction of commercial aqueous glyoxal is catalyzed by trifluoromethyl-substituted diarylprolinol 1 to afford a β-formyl-β-hydroxy-α-substituted aldehyde in good yield with excellent anti selectivity and excellent enantioselectivity.

Get access to the full text of this article

Ancillary