Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method (pages 946–949)
Fabricio R. Bisogno, Ana Rioz-Martínez, Cristina Rodríguez, Iván Lavandera, Gonzalo de Gonzalo, Daniel E. Torres Pazmiño, Marco W. Fraaije and Vicente Gotor
Article first published online: 28 JUN 2010 | DOI: 10.1002/cctc.201000115
Flying PIKATs: The stereoselective oxidation of several sulfides linked to the enantioselective oxidation of different sec-alcohols are combined in a parallel interconnected kinetic asymmetric transformation (PIKAT) fashion. Furthermore, the cofactor concentration employed in these processes is investigated, demonstrating a high capacity of performance, even at micromolar concentrations of the mediator.