This review is taken from a presentation at the From Genome to Life Summer School
Learning about gene regulatory networks from gene deletion experiments†
Article first published online: 12 DEC 2002
Copyright © 2002 John Wiley & Sons, Ltd.
Comparative and Functional Genomics
Volume 3, Issue 6, pages 499–503, December 2002
How to Cite
Schlitt, T. and Brazma, A. (2002), Learning about gene regulatory networks from gene deletion experiments. Comp Funct Genom, 3: 499–503. doi: 10.1002/cfg.220
- Issue published online: 12 DEC 2002
- Article first published online: 12 DEC 2002
- Manuscript Accepted: 14 OCT 2002
- Manuscript Received: 9 SEP 2002
- gene regulatory networks;
Gene regulatory networks are a major focus of interest in molecular biology. A crucial question is how complex regulatory systems are encoded and controlled by the genome. Three recent publications have raised the question of what can be learned about gene regulatory networks from microarray experiments on gene deletion mutants. Using this indirect approach, topological features such as connectivity and modularity have been studied. Copyright © 2002 John Wiley & Sons, Ltd.