Ontology for genome comparison and genomic rearrangements
Version of Record online: 6 JAN 2005
Copyright © 2004 John Wiley & Sons, Ltd.
Comparative and Functional Genomics
Volume 5, Issue 6-7, pages 537–544, August - October 2004
How to Cite
Flanagan, K., Stevens, R., Pocock, M., Lee, P. and Wipat, A. (2004), Ontology for genome comparison and genomic rearrangements. Comp Funct Genom, 5: 537–544. doi: 10.1002/cfg.436
- Issue online: 6 JAN 2005
- Version of Record online: 6 JAN 2005
- Manuscript Accepted: 1 NOV 2004
- Manuscript Revised: 27 OCT 2004
- Manuscript Received: 25 OCT 2004
We present an ontology for describing genomes, genome comparisons, their evolution and biological function. This ontology will support the development of novel genome comparison algorithms and aid the community in discussing genomic evolution. It provides a framework for communication about comparative genomics, and a basis upon which further automated analysis can be built. The nomenclature defined by the ontology will foster clearer communication between biologists, and also standardize terms used by data publishers in the results of analysis programs. The overriding aim of this ontology is the facilitation of consistent annotation of genomes through computational methods, rather than human annotators. To this end, the ontology includes definitions that support computer analysis and automated transfer of annotations between genomes, rather than relying upon human mediation. Copyright © 2004 John Wiley & Sons, Ltd.