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Keywords:

  • fragmentation mechanism;
  • glycine;
  • IRMPD (infrared multiple-photon dissociation);
  • mass spectrometry;
  • peptides
Thumbnail image of graphical abstract

Peptide patterns: The current experimental results indicate that infrared multiple-photon dissociation (IRMPD) of peptides forms more structurally informative sequence b and y ions, and fewer less useful nonsequence ions. Also the dissociation pathways are the same through excitation of different modes of the peptide. For the first time, it has been confirmed that the peptide dissociation pathway is not related to the initial protonation site or the conformation (e.g., cyclic or linear, see graphic) of the peptide.