Full Paper

Improvement of a Stereoselective Biocatalytic Synthesis by Substrate and Enzyme Engineering: 2-Hydroxy-(4′-oxocyclohexyl)acetonitrile as the Model

  1. Manuela Avi Dr.2,†,
  2. Romana M. Wiedner Dr.1,†,
  3. Herfried Griengl Prof.2,3,
  4. Helmut Schwab Prof.1,3

Article first published online: 12 NOV 2008

DOI: 10.1002/chem.200800609

Issue

Chemistry - A European Journal

Chemistry - A European Journal

Volume 14, Issue 36, pages 11415–11422, December 19, 2008

Additional Information

How to Cite

Avi, M., Wiedner, Romana M., Griengl, H. and Schwab, H. (2008), Improvement of a Stereoselective Biocatalytic Synthesis by Substrate and Enzyme Engineering: 2-Hydroxy-(4′-oxocyclohexyl)acetonitrile as the Model. Chem. Eur. J., 14: 11415–11422. doi: 10.1002/chem.200800609

Author Information

  1. 1

    Institute of Molecular Biotechnology, Graz University of Technology, Petersgasse 14, 8010 Graz (Austria), Fax: (+43) 316-873-4071

  2. 2

    Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 16, 8010 Graz (Austria)

  3. 3

    Research Centre Applied Biocatalysis, Petersgasse 14, 8010 Graz (Austria)

  1. †

    These authors contributed equally to the work.

  1. †

    These authors contributed equally to the work.

Publication History

  1. Issue published online: 12 DEC 2008
  2. Article first published online: 12 NOV 2008
  3. Manuscript Revised: 28 AUG 2008
  4. Manuscript Received: 2 APR 2008

Funded by

  • FWF Austrian Science Fund. Grant Numbers: I20-B03, I21-B03

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View Full Article (HTML) Get PDF (370K)