Probing the Surface of Organic and Bioconjugated Nanocrystals by Using Mass Spectrometric Imaging

Authors

  • Hyegeun Min,

    1. Nanobio Fusion Research Center, Korea Research Institute of Science and Standard, Daejeon 305-600 (Korea), Fax: (+82) 42-868-5032
    2. Department of Nano Surface Science, University of Science and Technology, Daejeon 305-333 (Korea)
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  • Yongwook Kim,

    1. Bio-Nanotechnology Center, Department of Chemistry, Pohang University of Science and Technology, Pohang, Kyungbuk 790-784 (Korea), Fax: (+82) 54-279-3399
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  • Hyunung Yu Dr.,

    1. Nanobio Fusion Research Center, Korea Research Institute of Science and Standard, Daejeon 305-600 (Korea), Fax: (+82) 42-868-5032
    2. Department of Nano Surface Science, University of Science and Technology, Daejeon 305-333 (Korea)
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  • Dae Won Moon Dr.,

    1. Nanobio Fusion Research Center, Korea Research Institute of Science and Standard, Daejeon 305-600 (Korea), Fax: (+82) 42-868-5032
    2. Department of Nano Surface Science, University of Science and Technology, Daejeon 305-333 (Korea)
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  • Sung Jun Lim,

    1. Bio-Nanotechnology Center, Department of Chemistry, Pohang University of Science and Technology, Pohang, Kyungbuk 790-784 (Korea), Fax: (+82) 54-279-3399
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  • Hye-Joo Yoon Dr.,

    1. Bio-Nanotechnology Center, Department of Chemistry, Pohang University of Science and Technology, Pohang, Kyungbuk 790-784 (Korea), Fax: (+82) 54-279-3399
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  • Tae Geol Lee Dr.,

    1. Nanobio Fusion Research Center, Korea Research Institute of Science and Standard, Daejeon 305-600 (Korea), Fax: (+82) 42-868-5032
    2. Department of Nano Surface Science, University of Science and Technology, Daejeon 305-333 (Korea)
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  • Seung Koo Shin Prof.

    1. Bio-Nanotechnology Center, Department of Chemistry, Pohang University of Science and Technology, Pohang, Kyungbuk 790-784 (Korea), Fax: (+82) 54-279-3399
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Abstract

original image

Mass fingerprints: Time-of-flight secondary ion mass spectrometry (TOF-SIMS) provides the mass fingerprint images of semiconductor nanocrystals in sizes of 6–12 nm self-assembled on a matrix-free substrate (see scheme). Organic ligands and DNA conjugated on nanocrystals yield micropatterns that overlap with those of nanocrystal materials. In contrast, other residual species display nanocrystal-free patterns.

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