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Highly Efficient Copper-Catalyzed Amidation of Aldehydes by C[BOND]H Activation

Authors

  • Long Wang,

    1. Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084 (China), Fax: (+86) 10-6278-1695
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  • Hua Fu Prof. Dr.,

    1. Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084 (China), Fax: (+86) 10-6278-1695
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  • Yuyang Jiang Prof. Dr.,

    1. Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084 (China), Fax: (+86) 10-6278-1695
    2. Key Laboratory of Chemical Biology (Guangdong Province), Graduate School of Shenzhen, Tsinghua University, Shenzhen 518057 (China)
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  • Yufen Zhao Prof. Dr.

    1. Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084 (China), Fax: (+86) 10-6278-1695
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Abstract

We have developed a highly efficient method for the copper-catalyzed amidation of aldehydes in the presence of N-bromosuccinimide (NBS). This method is simple, economical, and has practical advantages for synthesis of imides.

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