A Versatile Co(bisalen) Unit for Homogeneous and Heterogeneous Cooperative Catalysis in the Hydrolytic Kinetic Resolution of Epoxides

Authors

  • Krishnan Venkatasubbaiah Dr.,

    1. School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332 (USA), Fax: (+1) 404-894-2866
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  • Christopher S. Gill Dr.,

    1. School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332 (USA), Fax: (+1) 404-894-2866
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  • Tait Takatani,

    1. School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332 (USA)
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  • C. David Sherrill Prof. Dr.,

    1. School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332 (USA)
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  • Christopher W. Jones Prof. Dr.

    1. School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332 (USA), Fax: (+1) 404-894-2866
    2. School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA 30332 (USA)
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Abstract

Bisalen—very cooperative: A novel styryl-substituted, unsymmetrical bisalen is shown to be a versatile precursor to both soluble and insoluble cooperative catalysts for the hydrolytic kinetic resolution of epoxides. The unique bisalen motif ensures all catalysts derived from it have the necessary molecular-level ligand pairing needed for cooperative bimetallic catalytic reactions (see scheme).

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