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Keywords:

  • color chemistry;
  • DNA;
  • nanotubes;
  • peroxidases;
  • single nucleotide polymorphism
Thumbnail image of graphical abstract

SWNTs possess intrinsic peroxidase-like activity, catalyzing the reaction of peroxidase substrate 3,3,5,5-tetramethylbenzidene (TMB) in the presence of H2O2 to produce a color reaction. Here SWNTs have been used for label-free colorimetric detection of disease-associated single-nucleotide polymorphism with a direct detection limit of 1 nM.