Get access

Cover Picture: Controlling the Chair Conformation of a Mannopyranose in a Large-Amplitude [2]Rotaxane Molecular Machine (Chem. Eur. J. 21/2009)

Authors

  • Frédéric Coutrot Dr.,

    1. Institut des Biomolécules Max Mousseron (IBMM), UMR 5247CNRS-Universités Montpellier 2 et 1, Bâtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Chimie de Montpellier, 8, rue de l'Ecole Normale, 34296 Montpellier Cedex 5 (France), Fax: (+33) 467-14-43-44
    Search for more papers by this author
  • Eric Busseron

    1. Institut des Biomolécules Max Mousseron (IBMM), UMR 5247CNRS-Universités Montpellier 2 et 1, Bâtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Chimie de Montpellier, 8, rue de l'Ecole Normale, 34296 Montpellier Cedex 5 (France), Fax: (+33) 467-14-43-44
    Search for more papers by this author

Abstract

A domino effect from one extremity to the other is observed in a large-amplitude mannosyl [2]rotaxane molecular machine. In their Communication on page 5186 ff., F. Coutrot and E. Busseron describe the efficient preparation of new [2]rotaxane molecular machines containing anilinium and either mono- or disubstituted pyridinium amide stations. In the case of the disubstituted pyridinium amide, the macrocycle shuttles from the anilinium to the pyridinium upon deprotonation and causes an impressive flipping of the chair conformation of the glucidic moiety.

original image
Get access to the full text of this article

Ancillary