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Keywords:

  • allenes;
  • cross-coupling;
  • cyclization;
  • iron;
  • palladium
Thumbnail image of graphical abstract

New coupling: The interaction of ferric chloride with 2,3-allenoates generates a 2-(5H)-furanonyl iron species, which was observed to readily undergo transmetalation with PdCl2 to result in coupling with allylic bromides (see scheme). Based on this reaction, an efficient method for the synthesis of β-allyl polysubstituted butenolides from the easily available allylic bromides and 2,3-allenoates has been developed by using the cheap and readily available FeCl3 as the cocatalyst of PdCl2.