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Synthesis of Shape-Persistent Macrocycles by a One-Pot Suzuki–Miyaura Cross-Coupling Reaction



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Ring creation: Shape-persistent macrocyclic structures were prepared by a one-pot catalyst-transfer Suzuki–Miyaura cross-coupling (CTSMCC) reaction (see figure). The reaction of 3,6-dibromo-substituted carbazoles and diboronic ester monomers afforded shape-persistent macrocycles in yields of up to 67 %, whereas the use of a traditional catalyst gave the desired product only in a yield of about 16 %.