Get access
Advertisement

Bioinspired Catalyst Design and Artificial Metalloenzymes

Authors

  • Peter J. Deuss,

    1. School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST (UK), Fax: (+44) 1334463808
    Search for more papers by this author
  • Dr. René den Heeten,

    1. van't Hoff Institute for Molecular Sciences, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV, Amsterdam (The Netherlands)
    Search for more papers by this author
  • Dr. Wouter Laan,

    Corresponding author
    1. School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST (UK), Fax: (+44) 1334463808
    • School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST (UK), Fax: (+44) 1334463808
    Search for more papers by this author
  • Prof. Dr. Paul C. J. Kamer

    Corresponding author
    1. School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST (UK), Fax: (+44) 1334463808
    • School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST (UK), Fax: (+44) 1334463808
    Search for more papers by this author

Abstract

Many bioinspired transition-metal catalysts have been developed over the recent years. In this review the progress in the design and application of ligand systems based on peptides and DNA and the development of artificial metalloenzymes are reviewed with a particular emphasis on the combination of phosphane ligands with powerful molecular recognition and shape selectivity of biomolecules. The various approaches for the assembly of these catalytic systems will be highlighted, and the possibilities that the use of the building blocks of Nature provide for catalyst optimisation strategies are discussed.

Get access to the full text of this article

Ancillary