A privileged Glycon! A radical-addition Meerwein–Ponndorf–Verley (MPV) reduction sequence provides access to functionalized α-CF2-galactosides (see scheme). Introduction of a CF2Br group in the pseudo-anomeric position aided the transfer of an aglycon chain from O-2 to C-1′ through an intramolecular addition–reduction sequence, which involved a Br–Li exchange. This methodology gives access to a wide range of fluorinated C-glycosidic analogues of glycoconjugates.
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