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Keywords:

  • aziridines;
  • dithiocarbamates;
  • regioselectivity;
  • ring-opening;
  • synthetic methods
Thumbnail image of graphical abstract

Lord of the ring-opening! A metal-free strategy involving ring-opening of aziridines by the sodium salt of dialkyldithiocarbamate has been employed to give a variety of β-sulfonamido dithiocarbamates. The in situ generation of dialkyldithiocarbamates provided a simple, user-friendly, one-pot reaction that gives aziridine ring-opened products (see scheme; Ts=tosyl; R=alkyl; R1, R2=alkyl, cycloalkyl).