Luminescent Rhenium(I) Polypyridine Complexes Appended with an α-D-Glucose Moiety as Novel Biomolecular and Cellular Probes

Authors

  • Man-Wai Louie,

    1. Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
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  • Dr. Hua-Wei Liu,

    1. Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
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  • Marco Ho-Chuen Lam,

    1. Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
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  • Dr. Yun-Wah Lam,

    1. Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
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  • Dr. Kenneth Kam-Wing Lo

    Corresponding author
    1. Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
    • Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P.R. China), Fax: (+852) 3442-0522
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Abstract

original image

Glowing sweets! Three luminescent rhenium(I) polypyridine complexes have been modified with an α-D-glucose moiety. Their biomolecular binding, bacterial staining, and cellular-uptake properties have been examined (see figure). Various experimental results have indicated that glucose transporters play a very important role in the cellular uptake of these glucose complexes.

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