Communication

Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease III for the Regeneration of the Analyte

  1. Dr. Xiaoqing Liu†,
  2. Ronit Freeman†,
  3. Prof. Itamar Willner*

Article first published online: 25 JAN 2012

DOI: 10.1002/chem.201103342

Issue

Chemistry - A European Journal

Chemistry - A European Journal

Volume 18, Issue 8, pages 2207–2211, February 20, 2012

Additional Information

How to Cite

Liu, X., Freeman, R. and Willner, I. (2012), Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease III for the Regeneration of the Analyte. Chem. Eur. J., 18: 2207–2211. doi: 10.1002/chem.201103342

Author Information

  1. Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel), Fax: (+972) 2-6527715

  1. †

    These authors contributed equally to this study.

*Institute of Chemistry and the Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel), Fax: (+972) 2-6527715

Publication History

  1. Issue published online: 10 FEB 2012
  2. Article first published online: 25 JAN 2012
  3. Manuscript Received: 24 OCT 2011

Funded by

  • EU FP7 NANOGNOSTICS

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (614K)

Keywords:

  • amplification;
  • aptamers;
  • exonuclease;
  • fluorescence;
  • sensors
Thumbnail image of graphical abstract

Quick and easy detection: The Exo III-stimulated regeneration of the analyte by the digestion of supramolecular aptamer–analyte complexes provides a means to develop amplified optical aptasensors (see figure).

View Full Article with Supporting Information (HTML) Get PDF (614K)