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Keywords:

  • carbonylation;
  • heterocycles;
  • hydrazines;
  • palladium;
  • phthalazinones
Thumbnail image of graphical abstract

Phthalazinones made easy! A new, straightforward methodology for the carbonylative synthesis of phthalazinones has been established. Starting from readily available 2-bromobenzaldehydes or 2-bromoacetophenone and hydrazines, a variety of phthalazinones have been produced in good isolated yields (see scheme).