Functionalized Fe3O4 Nanoparticles for Detecting Zinc Ions in Living Cells and Their Cytotoxicity



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The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe3O4 nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn2+ over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn2+ levels in living cells (see figure).