Alkyne Hydrothiolation Catalyzed by a Dichlorobis(aminophosphine) Complex of Palladium: Selective Formation of cis-Configured Vinyl Thioethers

Authors

  • Roman Gerber,

    1. Department of Inorganic Chemistry, University of Zürich, 8057 Zürich (Switzerland), Fax: (+41) 44-635-46-92
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  • Dr. Christian M. Frech

    Corresponding author
    1. Department of Inorganic Chemistry, University of Zürich, 8057 Zürich (Switzerland), Fax: (+41) 44-635-46-92
    • Department of Inorganic Chemistry, University of Zürich, 8057 Zürich (Switzerland), Fax: (+41) 44-635-46-92
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Abstract

original image

Cis all round: Dichlorobis[1-(dicyclohexylphosphanyl)piperidine]palladium, [(P{(NC5H10)(C6H11)2})2Pd(Cl)2], is a highly efficient alkyne hydrothiolation catalyst and the first generally applicable system that selectively generates cis-configured anti-Markovnikov adducts in excellent yields within only a few minutes at 120 °C in the presence of only 0.05 mol % of the catalyst (see scheme).

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