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Keywords:

  • amino nitroolefins;
  • asymmetric catalysis;
  • bifunctional catalyst;
  • hydrosilylation;
  • reduction;
  • sulfinyl ureas
Thumbnail image of graphical abstract

Simple but effective: A structurally simple N-sulfinyl urea was found to be a highly efficient bifunctional catalyst, which allows for the development of a novel pathway for the construction of chiral β-amino nitroalkanes through enantioselective reduction of β-amino nitroolefins by trichlorosilane. High yields and excellent enantioselectivities were obtained for a broad range of β-arylamino nitroolefin substrates (see scheme).