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Keywords:

  • cross-coupling;
  • microreactors;
  • Suzuki–Miyaura coupling;
  • palladium
Thumbnail image of graphical abstract

Superflash! Flash chemistry enables the use of highly reactive unstable species as catalysts for chemical synthesis. Fast micromixing of a solution of [Pd(OAc)2] and that of tBu3P in 1:1 mole ratio gave a solution of a highly reactive unstable species, which was immediately transferred to a vessel by using a flow microreactor, in which Suzuki–Miyaura coupling was conducted (see scheme).