Terpyridine–Porphyrin Hetero-Pacman Compounds

Authors

  • Dr. Matthias Schwalbe,

    Corresponding author
    1. Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-St. 2, 12489 Berlin (Germany), Fax: (+49) 30-2093-6966
    • Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-St. 2, 12489 Berlin (Germany), Fax: (+49) 30-2093-6966
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  • Ramona Metzinger,

    1. Institut für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-St. 2, 12489 Berlin (Germany), Fax: (+49) 30-2093-6966
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  • Thomas S. Teets,

    1. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139-4307 (USA)
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  • Prof. Dr. Daniel G. Nocera

    1. Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139-4307 (USA)
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Abstract

The two different coordination spheres afforded by Pacman architectures offer cooperativity derived from two different metal centers. A modular strategy is developed to produce a hetero-Pacman scaffold featuring a porphyrin and terpyridine for metal-ion binding. A double Suzuki reaction was employed to first attach a terpyridine moiety to a xanthene backbone and then attach a porphyrin. The new hetero-Pacman scaffold has been characterized and all building blocks have been isolated and structurally characterized. The principle objective to incorporate different metal centers was confirmed by isolating a trinuclear complex comprising two porphyrinic units and a bis(terpyridine)–iron unit. The compounds described herein expand the Pacman scaffold concept by allowing for the incorporation of a terpyridine–metal complex proximate to a porphyrin-cofactor active site for small-molecule activation.

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