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Keywords:

  • aldehydes;
  • C[BOND]H activation;
  • imides;
  • palladium;
  • picolinamides

Abstract

An efficient palladium-catalyzed C[BOND]H functionalization of aldehydes with various N-substituted N-heteroarene-2-carboxamides has been developed for the synthesis of secondary imides. The reaction tolerates various functionalities, such as methoxy, fluoro, chloro, and bromo groups. A tentative radical mechanism for a PdII/PdIV catalytic cycle is proposed.