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Copper- and Phosphine-Ligand-Free Palladium-Catalyzed Direct Allylation of Electron-Deficient Polyfluoroarenes with Allylic Chlorides

Authors

  • Yan-Bo Yu,

    1. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai 200032 (P.R. China), Fax: (+86) 21-6416-6128
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  • Shilu Fan,

    1. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai 200032 (P.R. China), Fax: (+86) 21-6416-6128
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  • Prof. Dr. Xingang Zhang

    Corresponding author
    1. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai 200032 (P.R. China), Fax: (+86) 21-6416-6128
    • Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai 200032 (P.R. China), Fax: (+86) 21-6416-6128
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Abstract

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Simply id(all)ylic: A copper- and phosphine-ligand-free Pd-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides and the reaction mechanism are described (see scheme). The simple catalytic system, broad substrate scope, and excellent functional-group compatibility of this protocol provides a useful and facile access to allylated polyfluoroarenes.

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