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A DNA-Based and Electrochemically Transduced Keypad Lock System with Reset Function

Authors

  • Wei Hong,

    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
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  • Dr. Yan Du,

    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
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  • Tianshu Wang,

    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
    2. College of Physics, Jilin University, Changchun, Jilin 130012 (P. R. China)
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  • Jiyang Liu,

    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
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  • Dr. Yaqing Liu,

    Corresponding author
    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
    • State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
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  • Prof. Jin Wang,

    Corresponding author
    1. Department of Chemistry and Physics, State University of New York at Stony Brook, New York, NY 11794-3400 (USA)
    2. College of Physics, Jilin University, Changchun, Jilin 130012 (P. R. China)
    • Department of Chemistry and Physics, State University of New York at Stony Brook, New York, NY 11794-3400 (USA)
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  • Prof. Erkang Wang

    Corresponding author
    1. State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
    • State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P. R. China), Graduate School of the Chinese, Academy of Sciences, Beijing 100039 (P. R. China)
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Abstract

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Try your lock: A resettable DNA-based keypad lock system with electrochemical current as output signal has been successfully developed as proof of concept (see scheme). The system is triggered to ON only when the inputs are adopted with an appropriate combination and exact sequence. The reset function can be facilely realized.

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