In-spiro-ational: Biologically important and synthetically challenging spirocyclopentaneoxindoles with four consecutive stereocenters, including one spiroquaternary stereocenter, have been constructed in good yields and diastereoselectivity by a cascade reaction catalyzed by an N-heterocyclic carbene (see scheme). This reaction also provides a new strategy to access highly unusual tricyclic oxindoles.
If you can't find a tool you're looking for, please click the link at the top of the page to "Go to old article view". Alternatively, view our Knowledge Base articles for additional help. Your feedback is important to us, so please let us know if you have comments or ideas for improvement.