Rhodium-Catalyzed Carbocyclization and Chlorosulfonylation of 1,6-Enynes with Sulfonyl Chlorides

Authors

  • Chen Chen,

    1. Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Meilong Road, 130, Shanghai 200237 (P.R. China), Fax: (+86) 21-64253881
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  • Prof. Jianhua Su,

    1. Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Meilong Road, 130, Shanghai 200237 (P.R. China), Fax: (+86) 21-64253881
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  • Dr. Xiaofeng Tong

    Corresponding author
    1. Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Meilong Road, 130, Shanghai 200237 (P.R. China), Fax: (+86) 21-64253881
    • Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Meilong Road, 130, Shanghai 200237 (P.R. China), Fax: (+86) 21-64253881
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Abstract

original image

Linked in: A rhodium(I) catalyst system [[Rh(cod)Cl]+DPPF] enables carbocyclization and chlorosulfonylation of 1,6-enynes with sulfonyl chlorides, thus allowing the formation of three different bonds (C[BOND]Cl, C[BOND]C, and C[BOND]S) in a one-step fashion (see scheme; cod=cyclooctadiene, DPPF=1,1′-bis(diphenylphosphino)ferrocene). Sulfonyl chlorides are shown to be an efficient linker in this transformation, which complements other known element–element linkers.

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