Beauty lies in simplicity: An efficient and environmentally benign palladium-catalyzed protocol has been developed using a sulfinate as a nucleophilic coupling partner. The sulfinate position is arylated chemoselectively in very good yields. The bench-stable, non-hygroscopic heteroaromatic sulfinate salts rapidly undergo cross-coupling without the need of a co-catalyst, base, or additives (see scheme; mw=microwave).
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