Intermolecular Gold-Catalyzed Cycloaddition of Alkynes with Oxoalkenes

Authors

  • Carla Obradors,

    1. Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain)
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  • Prof. Antonio M. Echavarren

    Corresponding author
    1. Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain)
    2. Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/Marcel⋅li Domingo s/n, 43007 Tarragona (Spain)
    • Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona (Spain)
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Abstract

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As good as gold: Gold(I) catalyzes a new intermolecular reaction of terminal alkynes with functionalized alkenes that gives 8-oxabicyclo[3.2.1]oct-3-enes by a [2+2+2] cycloaddition process in which two C[BOND]C bonds and one C[BOND]O bond are formed (see scheme).

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