Microwave-Accelerated Ru-Catalyzed Hydrovinylation of Alkynes and Enynes: A Straightforward Approach toward 1,3-Dienes and 1,3,5-Trienes

Authors

  • Tobias Schabel,

    1. Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart (Germany), Fax: (+49) 711-68564285
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  • Prof. Dr. Bernd Plietker

    Corresponding author
    1. Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart (Germany), Fax: (+49) 711-68564285
    • Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart (Germany), Fax: (+49) 711-68564285
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Abstract

original image

Quick, but not dirty! Microwave heating was found to have a significant effect on the Ru-catalyzed hydrovinylations of alkynes. A broad range of different terminal alkynes were coupled to methyl acrylate within just 30 min in good to excellent yields (see scheme). This new protocol was transferred to the hydrovinylation of enynes as novel coupling partners in C[BOND]H-activation chemistry giving different 1,3,5-trienes as the sole products.

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