Palladium-Catalyzed Skeletal Rearrangement of Spirotricyclic Olefins: A Facile One-Pot Strategy for the Synthesis of a Novel Motif with Cyclopentene Fused to Benzofuran and Pyrazolidine

Authors

  • Praveen Prakash,

    1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
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  • Eliyan Jijy,

    1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
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  • Preethalayam Preethanuj,

    1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
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  • Prof. Dr. Petri M. Pihko,

    Corresponding author
    1. Department of Chemistry, University of Jyväskylä (Finland)
    • Department of Chemistry, University of Jyväskylä (Finland)
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  • Sarngadharan Sarath Chand,

    1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
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  • Dr. Kokkuvayil V. Radhakrishnan

    Corresponding author
    1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
    • Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR), Trivandrum 695019 (India), Fax: (+91) 471-491712
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Abstract

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Complex molecule synthesis: An efficient one-pot strategy for the synthesis of a novel framework of benzofuran-pyrazolidine-fused cyclopentenes by a palladium-catalyzed tandem reaction of cyclopropane-bearing spirotricyclic olefins with 2-iodophenols is reported (see scheme).

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