Cobalt-Catalyzed Hydrosilation/Hydrogen-Transfer Cascade Reaction: A New Route to Silyl Enol Ethers

Authors

  • Dr. Thomas W. Lyons,

    1. Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290 (USA), Fax: (+1) 919-962-3290
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  • Prof. Maurice Brookhart

    Corresponding author
    1. Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290 (USA), Fax: (+1) 919-962-3290
    • Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290 (USA), Fax: (+1) 919-962-3290

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Abstract

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Capitalizing on cobalt: A new route to silyl enol ethers employing a Co-catalyzed cascade reaction featuring a tandem hydrosilation/hydrogen-transfer reaction is reported. The low catalyst loading, mild reaction conditions, and unique η2-silane resting state showcase the impressive utility of this seldom used transition-metal catalyst in C[BOND]H activation reactions (see scheme; VTMS = vinyltrimethylsilane; Cp* = 1,2,3,4,5-pentamethylcyclopentadiene).

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