Multifunctional Hydroxyapatite Nanofibers and Microbelts as Drug Carriers (pages 6973–6982)
Zhiyao Hou, Piaoping Yang, Hongzhou Lian, Lili Wang, Cuimiao Zhang, Chunxia Li, Ruitao Chai, Ziyong Cheng and Jun Lin
Article first published online: 3 JUN 2009 | DOI: 10.1002/chem.200900269
Luminescent and mesoporous europium-doped hydroxyapatite (HAp:Eu3+) nanofibers and microbelts (see depicted SEM images) have been prepared by a combination of sol–gel and electrospinning processes with a cationic surfactant as the template. These multifunctional materials can be used as drug carriers, and drug release can be easily tracked and monitored by means of the change in Eu3+ luminescence intensity with released amount of drug.