Immunosuppressive Resveratrol Aneuploids from Hopea chinensis (pages 6338–6345)
Hui Ming Ge, Wen Hao Yang, Yan Shen, Nan Jiang, Zhi Kai Guo, Qiong Luo, Qiang Xu, Jing Ma and Ren Xiang Tan
Version of Record online: 21 APR 2010 | DOI: 10.1002/chem.201000230
Two resveratrol aneuploids, hopeachinols A (1) and B (2), and a potent immunosuppressive polyphenol diptoindonesin G (3) were characterized from Hopea chinensis. The structures were elucidated by comprehensive spectroscopic analysis and computational quantum-chemical methods. The distinct structure and immunosuppressive profile of 3 recommended it as a good starting molecule for relevant drug discovery.