Controlled Supramolecular Oligomerization of C3-Symmetrical Molecules in Water: The Impact of Hydrophobic Shielding (pages 5193–5203)
Dr. Pol Besenius, Dr. Kelly P. van den Hout, Harald M. H. G. Albers, Dr. Tom F. A. de Greef, Luuk L. C. Olijve, Dr. Thomas M. Hermans, Bas F. M. de Waal, Paul H. H. Bomans, Dr. Nico A. J. M. Sommerdijk, Dr. Giuseppe Portale, Dr. Anja R. A. Palmans, Dr. Marcel H. P. van Genderen, Dr. Jef A. J. M. Vekemans and Prof. Dr. E. W. Meijer
Article first published online: 22 MAR 2011 | DOI: 10.1002/chem.201002976
Chiral supramolecular oligomers of controlled shape in water: The aggregation concentration of amphiphilic C3-symmetrical discotics can be altered by modifying the number of secondary interactions and the solvophobic character of the polymerizing moieties (see picture). Hydrophobic shielding of the hydrogen-bonding motif in the core of the discotic is crucial for yielding stable, helical aggregates that are designed to be restricted in size through anti-cooperative, electrostatic repulsive interactions.