Chemistry - A European Journal

Cover image for Vol. 18 Issue 29

July 16, 2012

Volume 18, Issue 29

Pages 8849–9139

  1. Cover Picture

    1. Top of page
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    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Minireview
    7. Communications
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      Cover Picture: Full Exploration of the Diels–Alder Cycloaddition on Metallofullerenes M3N@C80 (M=Sc, Lu, Gd): The D5h versus Ih Isomer and the Influence of the Metal Cluster (Chem. Eur. J. 29/2012) (page 8849)

      Dr. Sílvia Osuna, Dr. Ramón Valencia, Dr. Antonio Rodríguez-Fortea, Prof. Marcel Swart, Prof. Miquel Solà and Prof. Josep M. Poblet

      Version of Record online: 10 JUL 2012 | DOI: 10.1002/chem.201290120

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      Endohedral metallofullerenes (EMFs) have attracted much more attention since the synthesis of the most abundant EMF, Sc3N@C80, in 1999 by Dorn and co-workers. In their Full Paper on page 8944 ff., A. Rodríguez-Fortea, M. Swart, M. Solà, J. M. Poblet et al. report a detailed theoretical analysis of the Diels–Alder cycloaddition of s-cis-1,3-butadiene on Sc3N@C80 and other related systems. Calculations show that the kinetic analysis is necessary to rationalize the reactivity properties of EMFs.

  2. Inside Cover

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    3. Inside Cover
    4. Graphical Abstract
    5. News
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    1. Inside Cover: Metal Ions Induce Growth and Magnetism Alternation of α-Fe2O3 Crystals Bound by High-Index Facets (Chem. Eur. J. 29/2012) (page 8850)

      Rongmei Liu, Yuanwen Jiang, Hao Fan, Prof. Qingyi Lu, Wei Du and Prof. Feng Gao

      Version of Record online: 10 JUL 2012 | DOI: 10.1002/chem.201290121

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      Quasi-cubic and dodecahedral α-Fe2O3 polyhedrons with different high-index facets exposed were synthesized by being induced with Zn2+ and Cu2+, respectively. These crystals were demonstrated to have shape- and surface-dependent magnetic behavior. For more details see the Full Paper by Q. Lu, F. Gao et al. on page 8957 ff.

  3. Graphical Abstract

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Minireview
    7. Communications
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  4. News

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Minireview
    7. Communications
    8. Full Papers
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  5. Minireview

    1. Top of page
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    3. Inside Cover
    4. Graphical Abstract
    5. News
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    1. Olefin Metathesis

      Removing Ruthenium Residues from Olefin Metathesis Reaction Products (pages 8868–8880)

      Dr. Georgios C. Vougioukalakis

      Version of Record online: 11 JUN 2012 | DOI: 10.1002/chem.201200600

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      Sequestering ruthenium impurities: Oxygen-, moisture-, and functional-group-tolerant ruthenium metathesis catalysts (see figure) have revolutionized the way synthetic chemists design and synthesize molecules. Nevertheless, the complete removal of ruthenium residues from olefin metathesis reaction products is often challenging. All kinds of strategies dealing with this problem are presented. The strengths and weaknesses of each method are thoroughly discussed.

  6. Communications

    1. Top of page
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    4. Graphical Abstract
    5. News
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    7. Communications
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    1. Domino Reactions

      Copper-Catalyzed Synthesis of Quinazolines in Water Starting from o-Bromobenzylbromides and Benzamidines (pages 8882–8885)

      Dr. Chandi C. Malakar, Dr. Alevtina Baskakova, Dr. Jürgen Conrad and Prof. Dr. Uwe Beifuss

      Version of Record online: 21 JUN 2012 | DOI: 10.1002/chem.201200583

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      Water makes it possible: The Cu2O-catalyzed reaction between easily available o-bromobenzylbromides and benzamidines by using Cs2CO3 as the base and N,N′-dimethylethylenediamine (DMEDA) as the additive in water as the solvent gives access to substituted quinazolines in a single step with yields ranging from 57 to 85 % (see scheme).

    2. Clusters

      Selective Construction of Pd2Pt and PdPt2 Triangles in a Sandwich Framework: Carbocyclic Ligands as Scaffolds for a Mixed-Metal System (pages 8886–8890)

      Prof. Tetsuro Murahashi, Kentaro Usui, Yuki Tachibana, Seita Kimura and Prof. Sensuke Ogoshi

      Version of Record online: 19 JUN 2012 | DOI: 10.1002/chem.201201474

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      Sandwich time! The mixed-metal triangular-trinuclear sandwich complexes of Pd2Pt and PdPt2 were selectively synthesized. The Pd2Pt and PdPt2 triangles in a cycloheptatrienyl sandwich framework were identified by 31P NMR analyses of the tris-triphenylphosphine complexes (see scheme).

    3. Asymmetric Catalysis

      Catalytic Enantioselective tert-Aminocyclization by Asymmetric Binary Acid Catalysis (ABC): Stereospecific 1,5-Hydrogen Transfer (pages 8891–8895)

      Liujuan Chen, Dr. Long Zhang, Dr. Jian Lv, Prof. Jin-Pei Cheng and Prof. Sanzhong Luo

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201201532

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      Selective H transfer by ABC: A new asymmetric binary acid catalyst was developed to promote 1,5-H transfer specifically and stereoselectively in tert-aminocyclization reactions with excellent activity, high enantioselectivity, and broad substrate scope. The H atom (in red) was proven to transfer through a stereospecific suprafacial pathway (see scheme).

    4. Heterocycles

      Synthesis of Aza-Fused Polycyclic Quinolines via Double C[BOND]H Bond Activation (pages 8896–8900)

      Ji-Rong Huang, Prof. Dr. Lin Dong, Dr. Bo Han, Prof. Dr. Cheng Peng and Prof. Dr. Ying-Chun Chen

      Version of Record online: 19 JUN 2012 | DOI: 10.1002/chem.201201207

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      Simple but efficient: Aza-fused polycyclic quinolines were efficiently assembled through rhodium(III)-based direct double C[BOND]H activation of N-aryl azoles followed by cyclization with alkynes without heteroatom-assisted chelation. Copper(II) acetate, aside from acting as an oxidant, could also play an important role in the C[BOND]H activation process.

    5. Homogeneous Catalysis

      Alkyne Hydrothiolation Catalyzed by a Dichlorobis(aminophosphine) Complex of Palladium: Selective Formation of cis-Configured Vinyl Thioethers (pages 8901–8905)

      Roman Gerber and Dr. Christian M. Frech

      Version of Record online: 14 JUN 2012 | DOI: 10.1002/chem.201200388

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      Cis all round: Dichlorobis[1-(dicyclohexylphosphanyl)piperidine]palladium, [(P{(NC5H10)(C6H11)2})2Pd(Cl)2], is a highly efficient alkyne hydrothiolation catalyst and the first generally applicable system that selectively generates cis-configured anti-Markovnikov adducts in excellent yields within only a few minutes at 120 °C in the presence of only 0.05 mol % of the catalyst (see scheme).

    6. Catalysis

      Nanoparticulate Peroxidase/Catalase Mimetic and Its Application (pages 8906–8911)

      Huimin Deng, Wei Shen, Yanfen Peng, Xiaojun Chen, Guangshun Yi and Zhiqiang Gao

      Version of Record online: 25 JUN 2012 | DOI: 10.1002/chem.201200643

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      Ru sitting comfortably: Ruthenium oxide nanoparticles show bienzyme-like activities, and are capable of catalyzing H2O2 disproportionation at pH 7.0 and peroxidation at pH 4.0 in aqueous solutions (see scheme). Their specific activities are better than many natural catalases and peroxidases and far better than bifunctional catalase/peroxidases.

    7. Zinc Catalysis

      A General and Efficient Zinc-Catalyzed Oxidation of Benzyl Alcohols to Aldehydes and Esters (pages 8912–8915)

      Dr. Xiao-Feng Wu

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201201105

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      Go green: A general and efficient zinc-catalyzed oxidation of benzyl alcohols has been developed. In the presence of a zinc catalyst, various aldehydes and esters have been prepared in good to excellent yields under mild conditions (see scheme).

    8. Asymmetric Synthesis

      Organocatalytic Enantioselective Stereoablative Hydroxylation of 3-Halooxindoles: An Effective Method for the Construction of Enantioenriched 3-Substituted 3-Hydroxy-2-Oxindoles (pages 8916–8920)

      Yu-Hua Liao, Dr. Zhi-Jun Wu, Wen-Yong Han, Prof. Dr. Xiao-Mei Zhang and Prof. Dr. Wei-Cheng Yuan

      Version of Record online: 19 JUN 2012 | DOI: 10.1002/chem.201201395

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      3-Substituted oxindoles as electrophilic partners: An unprecedented method for the construction of hydroxylated 3-substituted oxindoles in high yields and excellent enantioselectivities through stereoablative hydroxylation of 3-halooxindoles with an organocatalyst has been developed. This process not only differs from the common convention of using 3-substituted oxindoles as nucleophiles, but also provides a viable entry to optically active 3-substituted 3-hydroxy-2-oxindoles (see scheme).

    9. Sensors

      Aldehyde-Appended Distyrylbenzenes: Amine Recognition in Water (pages 8921–8924)

      Jan Kumpf and Prof. Uwe H. F. Bunz

      Version of Record online: 14 JUN 2012 | DOI: 10.1002/chem.201200930

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      Change in water: Aqueous solutions of aldehyde-substituted, water-soluble distyrylbenzenes reacted with amines to give imines or aminals with dramatically changed fluorescence. This approach allowed the detection and recognition of amines in water (see figure).

    10. Nanomachines

      Synthesis and STM Imaging of Symmetric and Dissymmetric Ethynyl-Bridged Dimers of Boron–Subphthalocyanine Bowl-Shaped Nanowheels (pages 8925–8928)

      Henri-Pierre Jacquot de Rouville, Romain Garbage, Dr. Francisco Ample, Anja Nickel, Joerg Meyer, Dr. Francesca Moresco, Dr. Christian Joachim and Prof. Dr. Gwénaël Rapenne

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201201123

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      The future's wheel: A new class of wheels, based on subphthalocyanine fragments, for future incorporation in functional nanovehicles is reported (see figure). The syntheses of a symmetric wheel, a nitrogen-tagged wheel, and their ethynyl-bridged homodimers are presented. Theoretical calculations and STM imaging demonstrate the advantage of a bowl-shaped structure and the efficiency of the tag for STM imaging.

    11. Cross-Coupling

      Facile Synthesis of meso-Arylamino- and Alkylaminosubporphyrins (pages 8929–8933)

      Masaaki Kitano, Shin-ya Hayashi, Dr. Takayuki Tanaka, Dr. Naoki Aratani and Prof. Dr. Atsuhiro Osuka

      Version of Record online: 19 JUN 2012 | DOI: 10.1002/chem.201201256

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      Newcomers: meso-Arylamino- and meso-alkylaminosubporphyrins have been synthesized by the Pd-catalyzed aminations of meso-bromosubporphyrin 1 as the first example of subporphyrins containing heteroatom substituents at the meso-position. The X-ray structural analyses have revealed significant structural distortions of meso-aminosubporphyrins 2 due to the effective electronic interaction (see scheme).

  7. Full Papers

    1. Top of page
    2. Cover Picture
    3. Inside Cover
    4. Graphical Abstract
    5. News
    6. Minireview
    7. Communications
    8. Full Papers
    9. Preview
    1. Aromatic Interactions

      Experimental Support for the Role of Dispersion Forces in Aromatic Interactions (pages 8934–8943)

      Dr. Carlos F. R. A. C. Lima, Marisa A. A. Rocha, Prof. Lígia R. Gomes, Prof. John N. Low, Prof. Artur M. S. Silva and Prof. Luís M. N. B. F. Santos

      Version of Record online: 22 JUN 2012 | DOI: 10.1002/chem.201201056

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      Dispersion rules! The intramolecular interaction enthalpy between the two aryl rings in various substituted 1,8-diphenylnaphthalenes was evaluated experimentally. The major factors ruling aromatic interactions in these systems are dispersion forces, rather than electrostatic forces. Quantifications of the true aromatic π⋅⋅⋅π interaction energy indicate that this type of interaction can be quite strong, even at nonoptimal interaction distances.

    2. Metallofullerenes

      Full Exploration of the Diels–Alder Cycloaddition on Metallofullerenes M3N@C80 (M=Sc, Lu, Gd): The D5h versus Ih Isomer and the Influence of the Metal Cluster (pages 8944–8956)

      Dr. Sílvia Osuna, Dr. Ramón Valencia, Dr. Antonio Rodríguez-Fortea, Prof. Marcel Swart, Prof. Miquel Solà and Prof. Josep M. Poblet

      Version of Record online: 12 JUN 2012 | DOI: 10.1002/chem.201200940

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      On the attack: An investigation of the exohedral reactivity of the most important and abundant endohedral metallofullerene, Sc3N@Ih-C80, its D5h counterpart Sc3N@D5h-C80, and lutetium- and gadolinium-based M3N@Ih/D5h-C80 (M=Lu, Gd) is provided. The thermodynamics and kinetics of the Diels–Alder cycloaddition of s-cis-1,3-butadiene on all the bonds of the Ih- and D5h-C80 cages (see figure) and their endohedral derivatives are analyzed.

    3. Crystal Engineering

      Metal Ions Induce Growth and Magnetism Alternation of α-Fe2O3 Crystals Bound by High-Index Facets (pages 8957–8963)

      Rongmei Liu, Yuanwen Jiang, Hao Fan, Prof. Qingyi Lu, Wei Du and Prof. Feng Gao

      Version of Record online: 22 JUN 2012 | DOI: 10.1002/chem.201201108

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      Ioned into shape: Two kinds of α-Fe2O3 polyhedrons, quasi-cube and hexagonal bipyramid (see SEM images), bound by high-index facets were controllably synthesized by applying metal ions Zn2+ or Cu2+ as structure-directing agents. The crystals display different magnetic properties.

    4. Quinoid Compounds

      Synthesis, Crystal Structures, and Properties of 6,12-Diaryl-Substituted Indeno[1,2-b]fluorenes (pages 8964–8970)

      Dr. Jun-ichi Nishida, Shingo Tsukaguchi and Prof. Dr. Yoshiro Yamashita

      Version of Record online: 12 JUN 2012 | DOI: 10.1002/chem.201200591

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      Substituent dependency: Fused polycyclic indeno[1,2-b]fluorene derivatives with aryl substituents have been prepared as a potential example of antiaromatic 20π electron systems (see scheme). X-ray analysis revealed quinoid-type molecular structures, which indicated that the bond lengths of the quinoid unit depend on the aryl substituents.

    5. Lithium Battery Performance

      Fabrication Based on the Kirkendall Effect of Co3O4 Porous Nanocages with Extraordinarily High Capacity for Lithium Storage (pages 8971–8977)

      Dr. Lin Hu, Dr. Nan Yan, Prof. Qianwang Chen, Ping Zhang, Hao Zhong, Xinrui Zheng, Yan Li and Xianyi Hu

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200770

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      Co3O4 porous nanocages have been prepared from Co3[Co(CN)6]2nH2O truncated nanocubes based on the Kirkendall effect (see figure). These nanocages overcome the intrinsic drawback of Co3O4 anodes and exhibit stable, high capacities with excellent cycling efficiency. Most importantly, this approach represents a technical advance, which is potentially competitive for scaling-up industrial production.

    6. Natural Products

      Asymmetric Synthesis of Pochonin E and F, Revision of Their Proposed Structure, and Their Conversion to Potent Hsp90 Inhibitors (pages 8978–8986)

      Dr. Ganesan Karthikeyan, Claudio Zambaldo, Dr. Sofia Barluenga, Dr. Vincent Zoete, Prof. Martin Karplus and Prof. Nicolas Winssinger

      Version of Record online: 13 JUN 2012 | DOI: 10.1002/chem.201200546

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      Cooling down the heat shock: Rapid access to pochonin E and F as well as their epimers at the allylic hydroxyl group established the correct stereochemistry of the natural product (see figure). The unnatural epimer afforded a more potent heat shock protein 90 (Hsp90) ligand, which stands as the most potent reported.

    7. Nanostructures

      Electrospun V2O5 Nanostructures with Controllable Morphology as High-Performance Cathode Materials for Lithium-Ion Batteries (pages 8987–8993)

      Dr. Heng-guo Wang, De-long Ma, Yun Huang and Prof. Dr. Xin-bo Zhang

      Version of Record online: 11 JUN 2012 | DOI: 10.1002/chem.201200434

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      Assault and batteries: Porous V2O5 nanotubes, hierarchical V2O5 nanofibers, and single-crystalline V2O5 nanobelts were controllably synthesized. When tested as the cathode materials in lithium-ion batteries, the as-formed V2O5 nanostructures exhibited highly reversible capacity, excellent cycling performance, and good rate capacity.

    8. Helical Structures

      Two-Component Fibers/Gels and Vesicles Formed from Hetero-Double-Helices of Pseudoenantiomeric Ethynylhelicene Oligomers with Branched Side Chains (pages 8994–9004)

      Dr. Nozomi Saito, Dr. Masanori Shigeno and Prof. Dr. Masahiko Yamaguchi

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200280

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      Fine-tunable assemblies: Two-component systems of pseudoenantiomeric ethynylhelicene pentamers and tetramers form gels in toluene and vesicles in diethyl ether. Properties of the assemblies can be fine-tuned by changing the combination of oligomers with different side chains. The pseudoenantiomeric oligomers form hetero-double-helices that hierarchically assemble to form fibers/gels and vesicles (see figure).

    9. Enantioselectivity

      Consecutive Intermolecular Reductive Hydroamination: Cooperative Transition-Metal and Chiral Brønsted Acid Catalysis (pages 9005–9010)

      Steffen Fleischer, Svenja Werkmeister, Dr. Shaolin Zhou, Dr. Kathrin Junge and Prof. Dr. Matthias Beller

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200109

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      The three musketeers! The enantioselective reductive hydroamination of alkynes with primary amines in the presence of molecular hydrogen as the reducing agent is demonstrated (see scheme). Key to success is the use of a three-component catalyst system consisting of a hydroamination, an imine activation, and a hydrogen activation catalyst.

    10. Ru Catalysis

      Phosphine–Imidazolyl Ligands for the Efficient Ruthenium-Catalyzed Hydrogenation of Carboxylic Esters (pages 9011–9018)

      Dr. Kathrin Junge, Bianca Wendt, Felix Alexander Westerhaus, Dr. Anke Spannenberg, Dr. Haijun Jiao and Prof. Dr. Matthias Beller

      Version of Record online: 25 JUN 2012 | DOI: 10.1002/chem.201200408

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      P-N the tail on the donkey: The combination of [{Ru(benzene)Cl2}2] and P-N ligand 1 e was active in the hydrogenation of aromatic esters and lactones, whilst [{Ru(benzene)Cl2}2]/1 c attained good results in the reduction of aliphatic lactones and esters (see scheme).

    11. Ionic Liquids

      Ionic-Liquid-Derived, Water-Soluble Ionic Cellulose (pages 9019–9023)

      Huyen Thanh Vo, Young Jin Kim, Eun Hee Jeon, Dr. Chang Soo Kim, Prof. Hoon Sik Kim and Dr. Hyunjoo Lee

      Version of Record online: 25 JUN 2012 | DOI: 10.1002/chem.201200982

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      Water works: The phosphorylation of cellulose with an ionic liquid, 1,3-dimethylimidazolium methylphosphite ([DMIm][(MeO)(H)PO2]), produced a highly water-soluble ionic cellulose (see figure) in which the repeating unit consists of a 1,3-dimethylimidazolium cation and a phosphite-substituted glucose anion.

    12. Peptides

      Effect of Residual Water and Microwave Heating on the Half-Life of the Reagents and Reactive Intermediates in Peptide Synthesis (pages 9024–9031)

      Dr. A. Pernille Tofteng, Dr. Søren L. Pedersen, Prof. Dan Staerk and Prof. Knud J. Jensen

      Version of Record online: 13 JUN 2012 | DOI: 10.1002/chem.201200711

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      Peptide couplings: Systematic studies of the rate of formation of activated esters by NMR spectroscopy (see figure) and their N-acylation during peptide synthesis were performed by using 13C-labeled Boc-Ala-OH. A study of the amount of residual water in the solvents revealed a significant effect on the electrophilic reagents and intermediates.

    13. Vitamin B12 Derivatives

      7-Decarboxymethyl-cobyrinates: Vitamin B12-Derivatives that Lack the c-Side Chain (pages 9032–9045)

      Dr. Bernhard Kräutler

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200830

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      Tinkering with B12: The Δ7-dehydro-cobyrinate pyrocobester is readily reduced to 7-decarboxymethyl-cobyrinates. These, in turn, are dehydrogenated by molecular oxygen to give back the Δ7-dehydro-cobyrinate pyrocobester. Thus, the redox environment determines the existence of either form of such corrinoids. Similar redox processes are inhibited by the characteristic substituents of the corrin moiety of vitamin B12 (see formula), helping to “chemically” rationalize the structures of B12-cofactors.

    14. Sandwich Complexes

      Sandwich Double-Decker Lanthanide(III) “Intracavity” Complexes Based on Clamshell-Type Phthalocyanine Ligands: Synthesis, Spectral, Electrochemical, and Spectroelectrochemical Investigations (pages 9046–9055)

      Dr. Victor E. Pushkarev , Dr. Alexander Yu. Tolbin, Fedor E. Zhurkin, Dr. Nataliya E. Borisova, Dr. Stanislav A. Trashin, Prof. Larisa G. Tomilova  and Prof. Nikolay S. Zefirov 

      Version of Record online: 19 JUN 2012 | DOI: 10.1002/chem.201200361

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      Clamshell phthalocyanine metal complexes were prepared by intramolecular reaction of a spacer-linked bis-ligand with a series of lanthanide(III) salts (see figure). Formation of high molecular weight oligophthalocyanine co-products was demonstrated as well. A combination of spectroscopic and electrochemical methods with theoretical calculations revealed that both the lanthanide cation and the spacer group affect the structure–property relationship.

    15. Glycoproteins

      Boronic Acid Functionalized Core–Shell Polymer Nanoparticles Prepared by Distillation Precipitation Polymerization for Glycopeptide Enrichment (pages 9056–9062)

      Yanyan Qu, Jianxi Liu, Dr. Kaiguang Yang, Dr. Zhen Liang, Prof. Dr. Lihua Zhang and Prof. Yukui Zhang

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201103514

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      Glycopeptides captured! Boronic acid functionalized core–shell polymer nanoparticles were synthesized to enrich glycopeptides. The core and shell were formed by distillation precipitation polymerization and free-radical polymerization, respectively (see scheme; AIBN=2,2′-azobisisobutyronitrile, MAA=methacrylic acid, MBA=methylenebisacrylamide, VPBA=4-vinylphenylboronic acid). The preparation of such nanoparticles is facile, time-saving, and the enrichment selectivity for glycopeptides is superior to the commercially available meta-aminophenylboronic acid agarose.

    16. Natural Products

      Synthetic Studies toward C-Glucosidic Ellagitannins: A Biomimetic Total Synthesis of 5-O-Desgalloylepipunicacortein A (pages 9063–9074)

      Dr. Gaëlle Malik, Dr. Anna Natangelo, Prof. Jaime Charris, Dr. Laurent Pouységu, Prof. Stefano Manfredini, Dr. Dominique Cavagnat, Dr. Thierry Buffeteau, Dr. Denis Deffieux and Prof. Stéphane Quideau

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200517

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      A route to C-glucosidic ellagitannins was exemplified by the synthesis of 5-O-desgalloylepipunicacortein A (see structure). The hexahydroxydiphenoyl unit of the natural product was either derived from ellagic acid or built atroposelectively. The key step was a biomimetic ring-opening C-arylglucosidation.

    17. Solid Solutions

      Study of Nanocrystalline BiMnO3--PbTiO3: Synthesis, Structural Elucidation, and Magnetic Characterization of the Whole Solid Solution (pages 9075–9082)

      Dr. Teresa Hungría, Covadonga Correas, Dr. Florent Houdellier, Dr. Octavio Peña, Dr. Eladio Vila and Prof. Dr. Alicia Castro

      Version of Record online: 1 JUN 2012 | DOI: 10.1002/chem.201200148

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      The whole truth: The preparation of the BiMnO3–PbTiO3 solid solution by mechanosynthesis has allowed the drawbacks of the synthesis to be solved, and light is shed on the remaining structural questions by precession electron diffraction. Magnetic characterization of the samples shows different behaviors depending on the composition (see figure), and these measurements are also useful in ascertaining the stability of this system.

    18. Natural Products

      Total Synthesis of a Noricumazole A Library and Evaluation of HCV Inhibition (pages 9083–9090)

      Dr. Jenny Barbier, Dr. Jens Wegner, Dr. Stefan Benson, Dr. Juliane Gentzsch, Prof. Dr. Thomas Pietschmann and Prof. Dr. Andreas Kirschning

      Version of Record online: 13 JUN 2012 | DOI: 10.1002/chem.201104042

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      Sulfur matters! A library of 16 noricumazole A derivatives was prepared by total synthesis. Noricumazole A is a strong inhibitor of the hepatitis C virus (HCV) life cycle but also shows pronounced cytotoxicity. In contrast, the new thiazole analogue (see structure) may be regarded as a lead structure with a good therapeutic index (CC50/IC50) of greater than 10.

    19. Helical Structures

      Hierarchical Superstructures with Control of Helicity from the Self-Assembly of Chiral Bent-Core Molecules (pages 9091–9098)

      Shih-Chieh Lin, Prof. Rong-Ming Ho, Chin-Yen Chang and Prof. Chain-Shu Hsu

      Version of Record online: 11 JUN 2012 | DOI: 10.1002/chem.201200057

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      Let's twist again: The helicity of twisted and helical ribbons was controlled by introducing chiral entities into bent-core molecules for their self-assembly. The formation of helical ribbons was attributed to the merging together of twisted ribbons (see figure).

    20. Peptide Conjugates

      Hierarchical Organization of Ferrocene–Peptides (pages 9099–9105)

      Samaneh Beheshti, Dr. Sanela Martić and Prof. Heinz-Bernhard Kraatz

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201200666

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      Twist and sheet! Ferrocene–peptide conjugates display self-association at the molecular and supramolecular levels that leads to the formation of microscopic-sized objects, such as cuboids, twisted ropes (see figure), and nanofiber networks.

    21. Silane Decomposition

      Thermal Decomposition of Branched Silanes: A Computational Study on Mechanisms (pages 9106–9116)

      Dr. Wilhelm A. Eger, Dr. Alexander Genest and Prof. Dr. Notker Rösch

      Version of Record online: 12 JUN 2012 | DOI: 10.1002/chem.201104015

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      Change of mechanism: Silanes with different silyl substitution patterns, representing increasing branching ratios, exhibit a change in the dominant mechanism of thermal decomposition from 1,2-H shift to homolytic dissociation at successively lower temperatures (see figure). This computational study traces in detail the influence of an increasing number of silyl residues.

    22. Controllable Reactions

      Solvent- and Temperature-Controlled In Situ Ligand Reactions Mediated by CuII and 3′-[(E)-{[(1S,2S)-2-Aminocyclohexyl]imino}methyl]-4′-hydroxy-4-biphenylcarboxlic Acid (pages 9117–9124)

      Qihui Chen, Feilong Jiang, Lian Chen, Ming Yang and Prof. Maochun Hong

      Version of Record online: 15 JUN 2012 | DOI: 10.1002/chem.201104001

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      Three new complexes were prepared by a solvent- and temperature-controlled in situ selective nitration of aromatic compounds (see figure). The mechanisms involved are discussed in detail.

    23. Electrochemical Capacitors

      Partially Reduced Graphite Oxide as an Electrode Material for Electrochemical Double-Layer Capacitors (pages 9125–9136)

      Moritz M. Hantel, Dr. Tommy Kaspar, Dr. Reinhard Nesper, Prof. Dr. Alexander Wokaun and Dr. Rüdiger Kötz

      Version of Record online: 14 JUN 2012 | DOI: 10.1002/chem.201200702

      Thumbnail image of graphical abstract

      GO to it: Partially reduced graphite oxide (GOpr) is a promising material for supercapacitor applications that employ organic electrolytes. It can be produced with distinct interlayer distances and chemical compositions by thermal reduction of graphite oxide, avoiding the need for any exfoliation or reassembly reaction. GOpr demonstrates a competitive specific capacitance that is superior to most of the various graphene-based electrodes (see figure; TEA+=tetraethylammonium).

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      Preview: Chem. Eur. J. 30/2012 (page 9139)

      Version of Record online: 10 JUL 2012 | DOI: 10.1002/chem.201290124

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