Stereochemical Studies on Ovatoxin-a (pages 16836–16843)
Prof. Patrizia Ciminiello, Dr. Carmela Dell'Aversano, Dr. Emma Dello Iacovo, Prof. Ernesto Fattorusso, Dr. Martino Forino, Dr. Laura Grauso and Dr. Luciana Tartaglione
Version of Record online: 29 OCT 2012 | DOI: 10.1002/chem.201201357
Ovatoxin-a stereostructure: The benthic dinoflagellate Ostreopsis ovata has bloomed across the Mediterranean basin over the past years, inflicting grave human and environmental suffering. The main toxin produced by O. ovata, ovatoxin-a, has been stereostructurally characterized by NMR techniques as a palytoxin analogue (see figure); this paves the way towards the evaluation of its toxicity.