Beta Sheets with a Twist: The Conformation of Helical Polyisocyanopeptides Determined by Using Vibrational Circular Dichroism (pages 13168–13174)
Dr. Erik Schwartz, Dr. Vincent Liégeois, Dr. Matthieu Koepf, Dr. Pavol Bodis, Prof. Dr. Jeroen J. L. M. Cornelissen, Dr. Patrick Brocorens, Dr. David Beljonne, Prof. Dr. Roeland J. M. Nolte, Prof. Dr. Alan E. Rowan, Dr. Sander Woutersen and Prof. Dr. Benoît Champagne
Article first published online: 12 AUG 2013 | DOI: 10.1002/chem.201300073
Good vibrations: The structure elucidation of helical polyisocyanides derived from alanylalanine (PIAA; see figure) by using a combination of DFT calculations and vibrational circular dichroism (VCD) spectroscopy is described. An accurate description of the conformation of the PIAA is attained, which contributes to the current understanding of the conformational architecture of polyisocyanides.