Heterocyclic Compounds
ChemInform Abstract: The Activity of Dispiro Peroxides Against Fasciola hepatica.
Article first published online: 9 DEC 2011
DOI: 10.1002/chin.201201149
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Wang, X., Zhao, Q., Vargas, M., Dong, Y., Sriraghavan, K., Keiser, J. and Vennerstrom, J. L. (2012), ChemInform Abstract: The Activity of Dispiro Peroxides Against Fasciola hepatica. ChemInform, 43: no. doi: 10.1002/chin.201201149
Publication History
- Issue published online: 9 DEC 2011
- Article first published online: 9 DEC 2011
- Abstract
- Article
- References
- Cited By
Keywords:
- other 6-membered heterocycles (with 3 or more heteroatoms);
- other 5-membered heterocycles (with 3 or more heteroatoms);
- antinematodal activity
Abstract
Dispiro peroxides (III),(VI),(VIII), and (X) are prepared either by coozonolysis of oxime ether (I) and ketoester (II), or by acid-catalyzed condensation of β-hydroperoxy alcohols (V) with adamantanone (IV) or cyclohexanone (IX), or by Re2O7-catalyzed condensation of dihydroperoxide esters (VII) with adamantanone (IV).

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