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Keywords:

  • alkylation;
  • chiral;
  • diastereoselective;
  • evans;
  • isotopomers;
  • kinetic resolution;
  • oxazolidinones;
  • profens;
  • 2-phenylpropionic acid

Abstract

A series of enantiomerically pure [D,13C]-labeled isotopomeric 2-phenylpropionic acids were efficiently synthesized using a diastereoselective alkylation and kinetic resolution strategy. Chirality, 2007. © 2007 Wiley-Liss, Inc.