Single-Use Technologies for Biopharmaceutical Production: Report from the Working Group Bioprocess Technology – Upstream Processing

Authors

  • Dr. Wolfram Meusel,

    Corresponding author
    1. Anhalt University of Applied Sciences, Department Applied Biosciences and Process Engineering, Bernburger Straße 55, 06366 Köthen/Anhalt, Germany
    • Anhalt University of Applied Sciences, Department Applied Biosciences and Process Engineering, Bernburger Straße 55, 06366 Köthen/Anhalt, Germany
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  • Jörg Kauling,

    1. Bayer Technology Service GmbH, 51368 Leverkusen, Germany
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  • Christian Löffelholz

    1. Zurich University of Applied Sciences, Department Life Sciences und Facility Management, 8820 Wädenswil, Switzerland
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Abstract

The main goal of the Bioprocess Technology working group is to overcome existing knowledge deficits in the bioprocess characterization of single-use bioreactors. The required methods have been investigated extensively, evaluated for their suitability for certain single-use bioreactors, and summarized into a basic structure in the so-called conceptual matrix. Development of standard operating procedures for the methods selected as well as their verification in interlaboratory tests guarantee that in the future a spectrum of unified and validated methods can be used to compare different bioreactor types objectively.

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