Project supported by the National Natural Science Foundation of China (Nos. 20025207, 20272071, 20372075, 20321202), the Chinese Academy of Sciences ("Knowledge Innovation" project, KGCX2-SW-209), and the Major State Basic Research Development Program (No. G2000077502) of China.
Synthesis and in vitro Antimalarial Activity of Several Simple Analogues of Peroxyplakoric Acid
Article first published online: 30 NOV 2005
Copyright © 2005 SIOC, CAS, Shanghai & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Chinese Journal of Chemistry
Volume 23, Issue 11, pages 1469–1473, November, 2005
How to Cite
Liu, H.-H., Jin, H.-X., Zhang, Q., Wu, Y.-K., Kim, H.-S. and Wataya, Y. (2005), Synthesis and in vitro Antimalarial Activity of Several Simple Analogues of Peroxyplakoric Acid. Chin. J. Chem., 23: 1469–1473. doi: 10.1002/cjoc.200591469
- Issue published online: 30 NOV 2005
- Article first published online: 30 NOV 2005
- Manuscript Accepted: 13 SEP 2005
- Manuscript Received: 31 MAY 2005
Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.