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Synthesis and Antimicrobial Activity of Some Condensed [4-(2,4,6-Trimethylphenyl)-1(2H)-oxo-phthalazin-2-yl]acetic Acid Hydrazide

  1. Maher A. El-Hashash1,
  2. Ahmed Y. El-Kady2,
  3. Mamdouh A. Taha2,
  4. Ibrahim E. El-Shamy2,*

Article first published online: 19 JAN 2012

DOI: 10.1002/cjoc.201100256

Issue

Chinese Journal of Chemistry

Chinese Journal of Chemistry

Volume 30, Issue 3, pages 616–626, March, 2012

Additional Information

How to Cite

El-Hashash, M. A., El-Kady, A. Y., Taha, M. A. and El-Shamy, I. E. (2012), Synthesis and Antimicrobial Activity of Some Condensed [4-(2,4,6-Trimethylphenyl)-1(2H)-oxo-phthalazin-2-yl]acetic Acid Hydrazide. Chin. J. Chem., 30: 616–626. doi: 10.1002/cjoc.201100256

Author Information

  1. 1

    Chemistry Department, Faculty of Science, Ain Shams University, Cairo, Egypt

  2. 2

    Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt

*Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt

Publication History

  1. Issue published online: 15 MAR 2012
  2. Article first published online: 19 JAN 2012
  3. Manuscript Accepted: 24 SEP 2011
  4. Manuscript Received: 18 AUG 2011

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Keywords:

  • 1(2H)-oxo-phthalazine;
  • 1,2,4-triazole;
  • 1,3,4-oxadiazole;
  • 1,3,4-thiadiazole;
  • antimicrobial activity

Abstract

Some new 1,2,4-triazolo-, 1,3,4-oxadiazolo-, 1,3,4-thiadiazol-, and pyrazolo-2,4,6-trimethylphenyl-1(2H)-oxo-phthalazine derivatives were synthesized and identified by IR, 1H NMR, 13C NMR, MS and elemental analysis. The new compounds were synthesized with the objective of studying their antimicrobial activity.

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