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Keywords:

  • lithium amidoborane;
  • reductive amination;
  • primary amines;
  • aldehydes;
  • ketones

Abstract

A variety of secondary amines were obtained in high isolated yields in the reductive amination of aldehydes and ketones by using lithium amidoborane as reducing agent. Compared to ammonia borane, lithium amidoborane has higher reducibility, and thus, exhibits faster reaction rate.