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Keywords:

  • indole;
  • aza-Wittig reaction;
  • iodine;
  • cyclization;
  • iminophosphorane

Abstract

3-Iodoindole N-carboximidamides and N-carboximidoates 4 were prepared regioselectively via a sequential aza-Wittig/iodine induced cyclization, starting from easily accessible 2-alkynylphenyl iminophosphorane, isocyanates, various nucleophiles and iodine.