SEARCH

SEARCH BY CITATION

Keywords:

  • thioamides;
  • oximes;
  • phorphorus pentasulfide;
  • Beckmann rearrangement;
  • iminocarbocation

Abstract

A facile and efficient approach to the synthesis of secondary thioamides from ketoximes via Beckmann rearrangement has been established, using phosphorus pentasulfide as a dehydrating and thiating agent. It is also efficient for the preparation of primary thiobenzamide from benzaldoxime. This approach features simple-operation, easy-control and good to excellent yields.