Non-covalently Functionalized Fluorescent Carbon Nanotubes: A Supramolecular Approach of Selective Zinc Ions Sensing in Living Cells

Authors

  • Miao Yu,

    1. Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
    2. Department of Chemistry and Chemical Engineering, Huanghuai University, Zhumadian, Henan 463000, China
    Search for more papers by this author
  • Yuping Liu,

    1. Research Center for Analytical Sciences, Nankai University, Tianjin 300071, China
    Search for more papers by this author
  • Yong Chen,

    1. Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
    Search for more papers by this author
  • Ning Zhang,

    1. Department of Chemistry and Chemical Engineering, Huanghuai University, Zhumadian, Henan 463000, China
    Search for more papers by this author
  • Yu Liu

    Corresponding author
    1. Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
    • Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China, Tel.: 0086-022-23503625; Fax: 0086-022-23503625
    Search for more papers by this author

Abstract

A fluorescent cyclodextrin/carbon nanotube assembly was easily constructed through the non-covalent attachment of adamantanylpyrene on carbon nanotube and the following association of cyclodextrin derivative bearing fluorescent substituent, and its structure was fully characterized by UV/Vis/NIR spectroscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, transmission electron microscopy and atomic force microscopy. Fluorescence spectroscopic and fluorescence microscopic studies showed that the resultant non-covalently functionalized fluorescent nanotube could be used as a highly selective fluorescent probe for Zn2+ in both water and living cells. Without carbon nanotube, the fluorescence probe was unable to enter the cell but only anchored on the cell membrane. This approach will overcome the disadvantage of many spectral sensors that are unable to enter living cells and greatly improve the application of naotube-related supramolecular architecture in nanoscience and technology.

Ancillary