Cu2+ Detection with Gold Nanoparticles by Patterning Colorimetric Strips on a Filter Membrane Assembled in a Microfluidic Chip

Authors

  • Yingyi Liu,

    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
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  • Jie Yu,

    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
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  • Wenwen Chen,

    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
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  • Dingbin Liu,

    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
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  • Zhuo Wang,

    Corresponding author
    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
    • CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China, Tel.: 0086-010-82545558; Fax: 0086-010-82545611
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  • Xingyu Jiang

    Corresponding author
    1. CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China
    • CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing 100190, China, Tel.: 0086-010-82545558; Fax: 0086-010-82545611
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Abstract

We have developed a microfluidic chip for colorimetric Cu2+ detection. In this chip, it is facile to do colorimetric Cu2+ detection based on gold nanoparticles. This method has a dynamic detection range from 0.75 to 50 µmol/L with only 20 µL solution including detection reagents and sample. The result can be readout by naked eye and photographed by digital cameras. With the help of image processing software, we could measure the RGB value and calculate the Blue/Red ratio for more accurate quantification. Tap water could be detected in this portable chip.

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